Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1782 | Thyroid cancer | ICEECE2012

Functional and molecular characterization of cancer stem cells in anaplastic thyroid carcinoma

Carina V. , Zito G. , Pizzolanti G. , Richiusa P. , Tomasello L. , Pitrone M. , Baiamonte C. , Guarnotta V. , Giordano C.

Anaplastic Thyroid Carcinoma (ATC) is the most aggressive thyroid gland malignancy characterized by undifferentiated morphology. It has been suggested that cancer stem cells (CSCs) might play a central role in ATC. Previously on the basis of CD133 positivity, our group suggested that CD133+ cancer stem cells (CSCs) might play a central role in ATC. Here we analyzed a panel of different stem cell markers in order to identify a peculiar CSC pattern in ATC....